Alternative treatment to the combination treatment of ticlopidine hydrochloride and ginkgo biloba extract when the effect of ticlopidine hydrochloride alone is insufficient for the following diseases: 1. Improvement of ischemic such as ulcer, pain and feeling cold accompanying chronic arterial insufficiency 2. Treatment of Ischemic cerebrovascular disease(thrombus and embolism accompanying transient cerebral ischemic attack (TIA), cerebral infarction) 3. Prevention and treatment of thrombosis and embolism due to coronary artery disease (angina pectoris, myocardial infarction) and treatment of ischemic symptoms 4. Prevention of Subacute stent thrombosis after stent implantation in coronary artery